Papers published in the OPR Working Paper Series reflect the view of individual authors. They may not be cited in other publications, but are intended to be work-in-progress. Comments are welcome. Background: Few studies focus on “preclinical ” warning signs associated with mortality. In this paper, we investigate associations between all-cause mortality and two clusters of biological risk factors: 1) standard clinical measures related to cardiovascular disease and metabolic function; and 2) nontraditional measures pertaining to hypothalamic-pituitary-adrenal axis activity, sympathetic nervous system activity and inflammatory response. Methods: Data come from the 2000 Social Environment and Biomarkers of Aging Study, a national sample of T...
Summary Because people age differently, age is not a sufficient marker of susceptibility to disabili...
Predicting longer-term mortality risk requires collection of clinical data, which is often cumbersom...
Associations of C-reactive protein (CRP) and fibrinogen with death may weaken over time. Combining b...
Background. Few studies focus on ‘‘preclinical’ ’ warning signs associated with mortality. In this a...
Researchers have had a longstanding interest in understanding the determinants of mortality. This ar...
Lifespan and the proportion of older people in the population are increasing, with far reaching cons...
BackgroundA goal of gerontology is discovering aging phenotypes that reflect biological aging distin...
The authors used data from a nationally representative survey of 933 adults aged 54 years or older (...
[[abstract]]Although some clinical and laboratory tests have been studied on their individual relati...
Background: Little is known about adult health and mortality relationships outside high-income natio...
<p>(A) HRs for all-cause mortality in a multivariate Cox model adjusted for age and sex, as well as ...
Purpose—In light of widespread interest in the prognostic value of biomarkers, we apply three discri...
<b>Background</b>: It has become increasingly common in multiple purpose general population surveys ...
BACKGROUND: Biomarkers may help clinicians predict cardiovascular risk. We aimed to determine if the...
Predicting longer-term mortality risk requires collection of clinical data, which is often cumbersom...
Summary Because people age differently, age is not a sufficient marker of susceptibility to disabili...
Predicting longer-term mortality risk requires collection of clinical data, which is often cumbersom...
Associations of C-reactive protein (CRP) and fibrinogen with death may weaken over time. Combining b...
Background. Few studies focus on ‘‘preclinical’ ’ warning signs associated with mortality. In this a...
Researchers have had a longstanding interest in understanding the determinants of mortality. This ar...
Lifespan and the proportion of older people in the population are increasing, with far reaching cons...
BackgroundA goal of gerontology is discovering aging phenotypes that reflect biological aging distin...
The authors used data from a nationally representative survey of 933 adults aged 54 years or older (...
[[abstract]]Although some clinical and laboratory tests have been studied on their individual relati...
Background: Little is known about adult health and mortality relationships outside high-income natio...
<p>(A) HRs for all-cause mortality in a multivariate Cox model adjusted for age and sex, as well as ...
Purpose—In light of widespread interest in the prognostic value of biomarkers, we apply three discri...
<b>Background</b>: It has become increasingly common in multiple purpose general population surveys ...
BACKGROUND: Biomarkers may help clinicians predict cardiovascular risk. We aimed to determine if the...
Predicting longer-term mortality risk requires collection of clinical data, which is often cumbersom...
Summary Because people age differently, age is not a sufficient marker of susceptibility to disabili...
Predicting longer-term mortality risk requires collection of clinical data, which is often cumbersom...
Associations of C-reactive protein (CRP) and fibrinogen with death may weaken over time. Combining b...