Lasers in Surgery and Medicine 32:160–170 (2003) Using a ‘‘Non Uniform Pulse Sequence’ ’ can Improve Selective Coagulation With a Nd:YAG Laser (1.06 mm) Thanks to Met-Hemoglobin Absorption: A Clinical Study on Blue Leg Veins

on 1–2 mm blue leg telangiectasia, of a 1,064 nm Nd:YAG laser emitting in a non uniform pulse sequence calculated to consider Met-Hb formation during laser irradiation of a blood vessel. Materials and Methods: A 1,064 nm Nd:YAG laser (Quantel Medical, Athos, France) was used in a non uni-form pulse sequence mode, fluences: 300–360 J/cm2 spot: 2 mm, þ 58C contact cooling. The clinical evaluation was performed on 11 female patients, average age: 43 (25–57) years, phototype I–VI. All subjects were previously exam-ined with Doppler ultrasound. A treatment site (6 4 cm) was selected on each patient. The topography of the vessels network was reported on a tracing plastic frame before each session and 6 weeks after the last one. These frames were digitized and the number of vessels was determined usin