dThe pattern of restenosis t

Background Edge restenosis is a major problem after radioactive stenting. The cold-end stent has a radioactive mid-segment (15·9 mm) and non-radioactive proximal and distal 5·7 mm segments. Conceptually this may negate the impact of negative vascular remodelling at the edge of the radiation. Method and Results ECG-gated intravascular ultrasound restenosis. Neointimal hyperplasia was inhibited in the area of radiation: neointimal hyperplasia=3·72 mm3 (8·6%); in-stent at the edges of radiation proximally and distally neointimal hyperplasia was 7·9 mm3 (19·0%) and 11·4 mm3 (25·6%), respectively (P=0·017). At the stent edges there was no significant change in lumen volume. Conclusions Cold-end stenting results in increased neointimal hyperplasia in in-stent non-radioactiv