Add to ORKGnetic factors play a role in the risk of stroke, particularly in younger individuals, but the role of single-nucleotide polymorphisms (SNPs) is controversial. We tested the possible association of a number of previously de-scribed SNPs with stroke risk. Methods: We investigated the prevalence of 60 poly-morphisms located in 35 genes in 450 white patients who suffered an acute stroke or transient ischemic attack before the age of 60 years and in 817 healthy control individuals by a multilocus PCR-based assay. The controls were randomly selected from attendees of a health service program. Genetic variations were de-tected by hybridization to nylon strips (Roche Molecu-lar Systems) containing detection oligonucleotides for the SNPs. We used P ...
BACKGROUND: The genes underlying the risk of stroke in the general population remain undetermined. M...
Our approach in identifying candidate genes for ischaemic stroke involved the selection and genotypi...
Evidence for a genetic basis for stroke comes from twin and family studies and from the occurrence o...
in inflammation-related genes have been linked to an increased risk of ischemic stroke. Most of thes...
Ischemic stroke is thought to have a polygenic basis, but identification of stroke susceptibility ge...
Familial aggregation of ischemic stroke derives from shared genetic and environmental factors. We pr...
in inflammation-related genes have been linked to an increased risk of ischemic stroke. Most of thes...
Familial aggregation of ischemic stroke derives from shared genetic and environmental factors. We pr...
Amy Z Fan1, Jing Fang1, Ajay Yesupriya2, Man-huei Chang2, Greta Kilmer1, Meaghan House3, Donald Haye...
Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown. We conduc...
The pathophysiology of stoke involves many complex pathways and risk factors. Though there are sever...
Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown. We conduc...
BACKGROUND: The genes underlying the risk of stroke in the general population remain undetermined. M...
Our approach in identifying candidate genes for ischaemic stroke involved the selection and genotypi...
Evidence for a genetic basis for stroke comes from twin and family studies and from the occurrence o...
in inflammation-related genes have been linked to an increased risk of ischemic stroke. Most of thes...
Ischemic stroke is thought to have a polygenic basis, but identification of stroke susceptibility ge...
Familial aggregation of ischemic stroke derives from shared genetic and environmental factors. We pr...
in inflammation-related genes have been linked to an increased risk of ischemic stroke. Most of thes...
Familial aggregation of ischemic stroke derives from shared genetic and environmental factors. We pr...
Amy Z Fan1, Jing Fang1, Ajay Yesupriya2, Man-huei Chang2, Greta Kilmer1, Meaghan House3, Donald Haye...
Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown. We conduc...
The pathophysiology of stoke involves many complex pathways and risk factors. Though there are sever...
Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown. We conduc...
BACKGROUND: The genes underlying the risk of stroke in the general population remain undetermined. M...
Our approach in identifying candidate genes for ischaemic stroke involved the selection and genotypi...
Evidence for a genetic basis for stroke comes from twin and family studies and from the occurrence o...