Effect of Long-Term Aluminium Chloride Intoxication on Selected Biochemical Parameters and Oxidative--Antioxidative Balance in Experimental Animals

Aluminium is numbered among trace elements with a moderate toxic effect on living organisms. We have attempted to assess the influence of long-term aluminium chloride intake on the biochemical param-eters and oxidative stress biomarkers in experimental animals. Three months ’ administration of aluminium chloride in drinking water at a dose of 80 mg/l significantly elevated blood serum urea and creatinine concentration, as well as oxidative stress biomarkers such as: TBARS content in erythrocytes hemolysate, protein carbonyl groups concentration and 8-hydroxy-2’-deoxyguanosine excretion with urine