IMPORTANCE Sickle cell disease (SCD) is a life-threatening genetic disorder affecting nearly 100 000 individuals in the United States and is associated with many acute and chronic complications requiring immediate medical attention. Two disease-modifying therapies, hydroxyurea and long-term blood transfusions, are available but underused. OBJECTIVE To support and expand the number of health professionals able and willing to provide care for persons with SCD. EVIDENCE REVIEW Databases of MEDLINE (including in-process and other nonindexed citations), EMBASE, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, CINAHL, TOXLINE, and Scopus were searched using prespecified search terms and keywords to identify...
Sickle cell disease (SCD) is common in Sudan and in sub-Saharan Africa. It is also prevalent in the ...
Sickle cell disease (SCD) is an autosomal reces-sive disorder due to a point mutation in the sixth c...
Background: Red cell transfusions remain a mainstay of therapy for patients with sickle cell disease...
Summary: Sickle cell disease (SCD) is a potentially devastating condition that is caused by an autos...
Abstract Background Sickle cell disease (SCD) is an inherited blood disorder that results in a lifet...
ObjectivesSickle cell disease (SCD) leads to chronic and acute complications that require specialise...
Although production of hemoglobin S, the genetic defect that causes sickle cell disease (SCD), direc...
Background: Previous natural history studies have advanced the understanding of sickle cell disease ...
Sickle cell disease (SCD) is an inherited disorder of hemoglobin structure that has no established c...
Sickle cell disease (SCD) is an inherited hematological disorder that can have a debilitating impact...
Objectives Sickle cell disease (SCD) leads to chronic and acute complications that require specialis...
BackgroundCentral nervous system (CNS) complications are among the most common, devastating sequelae...
Sickle cell disease is an autosomal recessive, multisystem disorder, characterised by chronic haemol...
Sickle cell disease is an autosomal recessive, multisystem disorder, characterised by chronic haemol...
Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal hemoglob...
Sickle cell disease (SCD) is common in Sudan and in sub-Saharan Africa. It is also prevalent in the ...
Sickle cell disease (SCD) is an autosomal reces-sive disorder due to a point mutation in the sixth c...
Background: Red cell transfusions remain a mainstay of therapy for patients with sickle cell disease...
Summary: Sickle cell disease (SCD) is a potentially devastating condition that is caused by an autos...
Abstract Background Sickle cell disease (SCD) is an inherited blood disorder that results in a lifet...
ObjectivesSickle cell disease (SCD) leads to chronic and acute complications that require specialise...
Although production of hemoglobin S, the genetic defect that causes sickle cell disease (SCD), direc...
Background: Previous natural history studies have advanced the understanding of sickle cell disease ...
Sickle cell disease (SCD) is an inherited disorder of hemoglobin structure that has no established c...
Sickle cell disease (SCD) is an inherited hematological disorder that can have a debilitating impact...
Objectives Sickle cell disease (SCD) leads to chronic and acute complications that require specialis...
BackgroundCentral nervous system (CNS) complications are among the most common, devastating sequelae...
Sickle cell disease is an autosomal recessive, multisystem disorder, characterised by chronic haemol...
Sickle cell disease is an autosomal recessive, multisystem disorder, characterised by chronic haemol...
Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal hemoglob...
Sickle cell disease (SCD) is common in Sudan and in sub-Saharan Africa. It is also prevalent in the ...
Sickle cell disease (SCD) is an autosomal reces-sive disorder due to a point mutation in the sixth c...
Background: Red cell transfusions remain a mainstay of therapy for patients with sickle cell disease...