In: Information Processing by Neuronal Populations. Ed(s) Christian

The sensorimotor model of hippocampal formation was last updated in a review by Bland and Oddie (2001). The model asserts that components of the neural circuitry in hippocampus and associated structures function in the capacity of providing voluntary motor systems with continually updated feedback on their performance relative to changing environmental (sensory) conditions. A crucial aspect of this performance is the intensity with which the motor programs are initiated and maintained. The components of the neural circuitry involved in sensorimotor integration are those underlying the production of oscillation and synchrony (theta) in the hippocampus and associated structures. Significant additions to the updated review included the description of the ascending brainstem hippocampal synchronizing pathways as the anatomical basis of the model, with the posterior hypothalamic region assigned the role of providing motor feedback to the hippocampal formation. A significant proportion of the nuclei contributing to the ascending brainstem hippocampal formation synchronizing pathways, up to and including the hippocampus, are cholinergic, cholinceptive, or both. The objective of the present chapter is to update the sensorimotor integration model, wit