PDF corresponds to the article as it appeared upon acceptance. Fully formatted PDF and full text (HTML) versions will be made available soon. Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells Genome Medicine 2014, 6:68 doi:10.1186/s13073-014-0068-
MutS and MutL are bacterial genes that have critical roles in DNA repair and recombination. Mutation...
During mismatch repair (MMR) MSH proteins bind to mismatches that form as the result of DNA replicat...
Cancer is a multigenic disease. The genetic distinctness of cancer cells offers a weakness that can ...
© 2014 Tosti et al.; licensee BioMed Central Ltd.Background: The evolutionarily conserved DNA mismat...
Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologo...
To date, cross-species comparisons of genetic interactomes have been restricted to small or function...
ao ro n DNA damage response (DDR) mechanisms to maintain pathway, non-homologous ends joining (NHEJ)...
In this study, we determined if BRCA1 partners involved in DNA double-strand break (DSB) and mismatc...
Recent genome sequencing efforts have revealed astounding genetic diversity between individuals in t...
To systematically identify genes that maintain genome structure, yeast knockout mutants were examine...
Contains fulltext : 148880.pdf (publisher's version ) (Open Access
In this study, we determined if BRCA1 partners involved in DNA double-strand break (DSB) and mismatc...
Genetic interaction and synthetic lethality are important tools that can be utilized to study the or...
The gene interactions govern the various biological processes and phenotype of biological organism.D...
Cancer cells are riddled with mutations. Less than one percent of these are thought to be mutations ...
MutS and MutL are bacterial genes that have critical roles in DNA repair and recombination. Mutation...
During mismatch repair (MMR) MSH proteins bind to mismatches that form as the result of DNA replicat...
Cancer is a multigenic disease. The genetic distinctness of cancer cells offers a weakness that can ...
© 2014 Tosti et al.; licensee BioMed Central Ltd.Background: The evolutionarily conserved DNA mismat...
Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologo...
To date, cross-species comparisons of genetic interactomes have been restricted to small or function...
ao ro n DNA damage response (DDR) mechanisms to maintain pathway, non-homologous ends joining (NHEJ)...
In this study, we determined if BRCA1 partners involved in DNA double-strand break (DSB) and mismatc...
Recent genome sequencing efforts have revealed astounding genetic diversity between individuals in t...
To systematically identify genes that maintain genome structure, yeast knockout mutants were examine...
Contains fulltext : 148880.pdf (publisher's version ) (Open Access
In this study, we determined if BRCA1 partners involved in DNA double-strand break (DSB) and mismatc...
Genetic interaction and synthetic lethality are important tools that can be utilized to study the or...
The gene interactions govern the various biological processes and phenotype of biological organism.D...
Cancer cells are riddled with mutations. Less than one percent of these are thought to be mutations ...
MutS and MutL are bacterial genes that have critical roles in DNA repair and recombination. Mutation...
During mismatch repair (MMR) MSH proteins bind to mismatches that form as the result of DNA replicat...
Cancer is a multigenic disease. The genetic distinctness of cancer cells offers a weakness that can ...