Next-generation sequencing technologies are increasing our ability to study genome function. A new and rapidly growing family of assays for measuring the genome-wide profiles of mRNAs, small RNAs, transcription-factor binding, chromatin structure and DNA methylation status are now being implemented by applying the massively parallel, ultrahigh-throughput DNA sequencing systems. These rapid growths demand reliable, fast and easy-to-use analysis tools. We present the SeqMapReduce software for parallelizing sequence mapping using the cloud computing technology. The speed is quasi-linear to the number of computing nodes available. It took 4.5 minutes to map 6 million sequence reads to the human genome with 32 computing nodes. A comparison betwe...
Over the last decade more data has been produced than in the entire human civilization. Advances in ...
Advances in DNA sequencing revolutionized the field of genomics over the last 5 years. New sequencin...
Order 3 billion base pairs of DNA in the correct order and you get the blueprint of a human, the gen...
Abstract Background Since the introduction of next-generation DNA sequencers the rapid increase in s...
Summary: SeqMap is a tool for mapping large amount of short sequences to the genome. It is designed ...
Summary: Many time-consuming analyses of next-generation sequencing data can be addressed with moder...
Motivation: Next-generation DNA sequencing machines are generating an enormous amount of sequence da...
<div><p>The increasing public availability of personal complete genome sequencing data has ushered i...
Background: Decreasing costs make RNA sequencing technologies increasingly affordable for biologists...
Better protocols and decreasing costs have made high-throughput sequencing experiments now accessibl...
Many time-consuming analyses of next -: generation sequencing data can be addressed with modern clou...
Background: While next-generation sequencing (NGS) technologies are rapidly advancing, an area that ...
A revolution in personalized genomics will occur when scientists can sequence genomes of millions of...
Recent advances in sequencing technology have created unprecedented opportunities for biological res...
Abstract Background High-throughput automated sequencing has enabled an exponential growth rate of s...
Over the last decade more data has been produced than in the entire human civilization. Advances in ...
Advances in DNA sequencing revolutionized the field of genomics over the last 5 years. New sequencin...
Order 3 billion base pairs of DNA in the correct order and you get the blueprint of a human, the gen...
Abstract Background Since the introduction of next-generation DNA sequencers the rapid increase in s...
Summary: SeqMap is a tool for mapping large amount of short sequences to the genome. It is designed ...
Summary: Many time-consuming analyses of next-generation sequencing data can be addressed with moder...
Motivation: Next-generation DNA sequencing machines are generating an enormous amount of sequence da...
<div><p>The increasing public availability of personal complete genome sequencing data has ushered i...
Background: Decreasing costs make RNA sequencing technologies increasingly affordable for biologists...
Better protocols and decreasing costs have made high-throughput sequencing experiments now accessibl...
Many time-consuming analyses of next -: generation sequencing data can be addressed with modern clou...
Background: While next-generation sequencing (NGS) technologies are rapidly advancing, an area that ...
A revolution in personalized genomics will occur when scientists can sequence genomes of millions of...
Recent advances in sequencing technology have created unprecedented opportunities for biological res...
Abstract Background High-throughput automated sequencing has enabled an exponential growth rate of s...
Over the last decade more data has been produced than in the entire human civilization. Advances in ...
Advances in DNA sequencing revolutionized the field of genomics over the last 5 years. New sequencin...
Order 3 billion base pairs of DNA in the correct order and you get the blueprint of a human, the gen...