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a, correlation between TNF-α levels and the visceral to subcutaneous fat ratio (r = 0.42, P b.02) and a negative correlation between adiponectin Available online at www.sciencedirect.com Metabolism Clinical and Experimentalevel and the visceral to subcutaneous fat ratio (r = −0.69, P b.001). Despite the limitation of sample size, our results indicate that the observed massive weight loss (mainly visceral fat) was highly correlated with a decreased inflammatory state, suggesting that the interdisciplinary therapy was effective in decreasing inflammatory markers. © 2011 Elsevier Inc. All rights reserved. 1