Add to ORKG(Communicated by) Abstract. Mathematical models for cancer chemotherapy as optimal con-trol problems are considered. Results on scheduling optimal therapies when the controls represent the effectiveness of chemotherapeutic agents, or, equiva-lently, when the simplifying assumption is made that drugs act instantaneously, are compared with more realistic models that include pharmacokinetic (PK) equations modelling the drug’s plasma concentration and various pharmaco-dynamic (PD) models for the effect the concentrations have on cells. 1. Introduction. Mathematica
A system of differential equations for the control of tumour cell growth in a cyclenonspecific chemo...
Abstract — A mathematical model for the scheduling of an-giogenic inhibitors in combination with a k...
Cancer is the name given to a class of diseases characterized by an imbalance in cell proliferation ...
Abstract: Phase specific models for cancer chemotherapy are described as optimal control problems. W...
An optimal control problem for an abstract mathematical model for cancer chemotherapy is considered....
A mathematical model for the depletion of bone marrow under cancer chemotherapy is analyzed as an op...
An optimal parameter selection model of cancer chemotherapy is presented which describes the treatme...
We review mathematical results about the qualitative structure of chemotherapy protocols that were o...
We develop a mathematical model to simulate the effects of a cell-cycle-specific chemotherapy like p...
A system of differential equations for the control of tumor cells growth in a cycle nonspecific chem...
We develop a mathematical model to simulate the effects of a cell-cycle-specific chemotherapy like p...
(Communicated by Aim Sciences) Abstract. We analyze non cell-cycle specific mathematical models for ...
A system of differential equations for the control of tumor cells growth in a cycle nonspecific chem...
A system of differential equations for the control of tumor growth cellsin a cycle non-specific chem...
Abstract. Optimal control techniques are usedto develop optimal strategies for chemotherapy. In part...
A system of differential equations for the control of tumour cell growth in a cyclenonspecific chemo...
Abstract — A mathematical model for the scheduling of an-giogenic inhibitors in combination with a k...
Cancer is the name given to a class of diseases characterized by an imbalance in cell proliferation ...
Abstract: Phase specific models for cancer chemotherapy are described as optimal control problems. W...
An optimal control problem for an abstract mathematical model for cancer chemotherapy is considered....
A mathematical model for the depletion of bone marrow under cancer chemotherapy is analyzed as an op...
An optimal parameter selection model of cancer chemotherapy is presented which describes the treatme...
We review mathematical results about the qualitative structure of chemotherapy protocols that were o...
We develop a mathematical model to simulate the effects of a cell-cycle-specific chemotherapy like p...
A system of differential equations for the control of tumor cells growth in a cycle nonspecific chem...
We develop a mathematical model to simulate the effects of a cell-cycle-specific chemotherapy like p...
(Communicated by Aim Sciences) Abstract. We analyze non cell-cycle specific mathematical models for ...
A system of differential equations for the control of tumor cells growth in a cycle nonspecific chem...
A system of differential equations for the control of tumor growth cellsin a cycle non-specific chem...
Abstract. Optimal control techniques are usedto develop optimal strategies for chemotherapy. In part...
A system of differential equations for the control of tumour cell growth in a cyclenonspecific chemo...
Abstract — A mathematical model for the scheduling of an-giogenic inhibitors in combination with a k...
Cancer is the name given to a class of diseases characterized by an imbalance in cell proliferation ...