Terahertz Time-Domain Spectroscopy of Glucose and Uric

Abstract. We report the use of terahertz time-domain spectroscopy for the study of two therapeutic bio-molecules: glucose and uric acid. Terahertz transmission spectra of crystalline samples of both molecules were measured between 0.1–3.0 THz using an evacuated spectroscopy system. We propose that the stereo-isomers of glucose show spectral features originating from intermolecular vibrational modes, as do uric acid and its derivative molecule, allantoin. In addition, we present a full temperature dependence of the terahertz absorption of L-glucose