Metabolism of Pyrethroids by Mosquito Cytochrome P450 Enzymes: Impact on Vector Control

Cytochrome P450 enzymes (P450s) are heme-containing monooxygenases that catalyze metabolisms of various endogenous and exogenous compounds. These P450s constitute a superfamily of enzymes present in various organisms including mammals, plants, bacteria, and insects. P450 enzymes are diverse and metabolize a wide variety of substrates, but thei