Magnetic Stimulation of Neural Tissue: Techniques and System Design

Abstract Magnetic stimulation of neural tissue is an attractive technology because neural excitationmay be affected without the implantation of electrodes. This chapter provides a brief overview of the technology and relevant literature. While extensive magnetic stimulation modeling and clinical experimentation work has been presented, considerably less quantitative in vitro work has been performed. In vitro experiments are critical for characterizing the site of action, the structures stimulated, and the long-term tissue histological effects. In vitro systems may also facilitate the development of novel magnetic stimulation approaches. To demystify magnetic stimulation systems, this chapter presents an in vitro experimental system using a systematic design methodology. The modeling methods are designed to aid experimentation. Circuit schematics, test rigs, and supplier information are given to support practical implementation of this design methodology. Example neural preparations and their modeling and use are also covered. Finally, as an alternative to pulsed discharge circuits for magnetic stimulation, this chapter shows how to use a circuit to deliver asym-metric current pulses to generate the magnetic field.