Abstract Largest satellite of Saturn and the only in the solar system having a dense atmo-sphere, Titan is one of the key planetary bodies for astrobiological studies, due to several aspects. (i) Its analogies with planet Earth, in spite of much lower temperatures, with, in par-ticular, a methane cycle on Titan analogous to the water cycle on Earth. (ii) The presence of an active organic chemistry, involving several of the key compounds of prebiotic chemistry. The recent data obtained from the Huygens instruments show that the complex organic matter in Titan’s low atmosphere is mainly concentrated in the aerosol particles. The formation of biologically interesting compounds may also occur in the deep water ocean, from the hydrolysis of comp...