Add to ORKGComputer-aided approaches have been widely used in pharmaceutical research to improve the efficiency of the drug discovery and development pipeline. To identify and design small molecules as clinically effective therapeutics, various computational methods have been evaluated as promising strategies, depending on the purpose and systems of interest. Both ligand and structure-based drug design approaches are powerful technologies, which can be applied to virtual screening for lead identification and optimization. Here, we review the progress in this field and summarize the application of some new technologies we developed. These state-of-the-art tools have been used for the discovery and develop-ment of active agents for various diseases, in ...
Background: Drug approval applications to the FDA have shown a remarkably small increment compared w...
Discovery and development of a new drug is generally known as a very complex process which takes a l...
The conventional drug discovery approach is an expensive and time-consuming process, but its limitat...
Drug discovery utilizes chemical biology and computational drug design approaches for the efficient ...
The process of discovering and developing a new medication is often seen as a lengthy and expensive ...
Computational approaches are an integral part of interdisciplinary drug discovery research. Understa...
The process for drug discovery and development is challenging, time consuming and expensive. Compute...
Traditional drug design requires a great amount of research time and developmental expense. Booming ...
Cancer is considered as one of the world\u27s leading causes of morbidity and mortality. Over the pa...
Computer-aided drug discovery techniques reduce the time and the costs needed to develop novel drugs...
In silico methodologies have become an essential part of the modern drug discovery process. This the...
The use of computer-aided drug design (CADD) for the identification of lead compounds in radiotracer...
The escalating prevalence of cancer on a global scale, coupled with the inadequacies of present-day ...
Bioinformatics and chemoinformatics approaches contribute to hit discovery, hit-to-lead optimization...
It is widely accepted that the design of a novel drug is a challenging, time-consuming and very expe...
Background: Drug approval applications to the FDA have shown a remarkably small increment compared w...
Discovery and development of a new drug is generally known as a very complex process which takes a l...
The conventional drug discovery approach is an expensive and time-consuming process, but its limitat...
Drug discovery utilizes chemical biology and computational drug design approaches for the efficient ...
The process of discovering and developing a new medication is often seen as a lengthy and expensive ...
Computational approaches are an integral part of interdisciplinary drug discovery research. Understa...
The process for drug discovery and development is challenging, time consuming and expensive. Compute...
Traditional drug design requires a great amount of research time and developmental expense. Booming ...
Cancer is considered as one of the world\u27s leading causes of morbidity and mortality. Over the pa...
Computer-aided drug discovery techniques reduce the time and the costs needed to develop novel drugs...
In silico methodologies have become an essential part of the modern drug discovery process. This the...
The use of computer-aided drug design (CADD) for the identification of lead compounds in radiotracer...
The escalating prevalence of cancer on a global scale, coupled with the inadequacies of present-day ...
Bioinformatics and chemoinformatics approaches contribute to hit discovery, hit-to-lead optimization...
It is widely accepted that the design of a novel drug is a challenging, time-consuming and very expe...
Background: Drug approval applications to the FDA have shown a remarkably small increment compared w...
Discovery and development of a new drug is generally known as a very complex process which takes a l...
The conventional drug discovery approach is an expensive and time-consuming process, but its limitat...