Add to ORKGThe primary departmental goal of preclinical toxicology (a.k.a. safety assessment) in drug development is to identify and characterize drug-induced toxicity in test animals by using appropriate animal models. This is accomplished through a large numbe
The thalidomide tragedy stimulated an intense research in the etiology, prevention and treatment of ...
Preclinical studies and testing strategies with and without the use of animal testing methods have t...
The current approach to human health risk assessment is an integrated approach requiring a significa...
New developments in flow cytometry are now being applied in toxicology studies. There are several re...
The worldwide rapid increase in bacterial resistance to numerous antibiotics requires on-going devel...
The process of new drug development consists of several stages; after identifying potential candidat...
Proper preclinical safety evaluation can improve the predictive value, lessen the time and cost of l...
Rapid screening of industrial compounds for toxicity will require high-throughput in vitro assays wi...
The worldwide rapid increase in bacterial resistance to numerous antibiotics requires on-going devel...
Efficient and accurate safety assessment of compounds is extremely important in the preclinical deve...
The qualitative or quantitative extrapolation of preclinical data to man and the accuracy of predict...
Currently, much effort is invested into the development of non-animal testing strat-egies to identif...
Toxicity testing is critical in the evaluation of novel medications before they are used on humans. ...
In vitro cytotoxicity assays can be used as alternative toxicity tests to reduce the total number of...
The replacement of animals in acute systemic toxicity testing remains a considerable challenge. Only...
The thalidomide tragedy stimulated an intense research in the etiology, prevention and treatment of ...
Preclinical studies and testing strategies with and without the use of animal testing methods have t...
The current approach to human health risk assessment is an integrated approach requiring a significa...
New developments in flow cytometry are now being applied in toxicology studies. There are several re...
The worldwide rapid increase in bacterial resistance to numerous antibiotics requires on-going devel...
The process of new drug development consists of several stages; after identifying potential candidat...
Proper preclinical safety evaluation can improve the predictive value, lessen the time and cost of l...
Rapid screening of industrial compounds for toxicity will require high-throughput in vitro assays wi...
The worldwide rapid increase in bacterial resistance to numerous antibiotics requires on-going devel...
Efficient and accurate safety assessment of compounds is extremely important in the preclinical deve...
The qualitative or quantitative extrapolation of preclinical data to man and the accuracy of predict...
Currently, much effort is invested into the development of non-animal testing strat-egies to identif...
Toxicity testing is critical in the evaluation of novel medications before they are used on humans. ...
In vitro cytotoxicity assays can be used as alternative toxicity tests to reduce the total number of...
The replacement of animals in acute systemic toxicity testing remains a considerable challenge. Only...
The thalidomide tragedy stimulated an intense research in the etiology, prevention and treatment of ...
Preclinical studies and testing strategies with and without the use of animal testing methods have t...
The current approach to human health risk assessment is an integrated approach requiring a significa...