Hodgkin Lymphoma, Multiple Myeloma, Soft Tissue Sarcomas, Insect Repellents,

Objective: The objective of this study was to determine if there is an additional risk of developing Hodgkin lymphoma, multiple myeloma, or soft tissue sarcoma as a consequence of exposure to a combination of phenoxyherbicides, rubber gloves, DEET (N, N-diethyl-m-toluamide), and sunlight compared with each of the individual chemicals.Methods: This was a population-based study of men with specific cancers and age, province-matched control subjects. Results: No additional risk from these combinations of exposures of developing these three types of tumor was found in contrast to non-Hodgkin lymphoma. Conclusions: The mech-anisms by which phenoxyherbicides contribute to the risk of multiple myeloma and non-Hodgkin lymphoma may be different. (J Occup Environ Med. 2006;48:264–274) T he safety and efficacy of insect re-pellents containing DEET (N, N-diethyl-m-toluamide) as the activeingredient have been investigated ex-tensively in recent years, although these products have been in wide