Add to ORKGI, Matthew Robert Symes, confirm that this dissertation and the work presented in it are my own achievement. Where I have consulted the published work of others this is always clearly attributed; Where I have quoted from the work of others the source is always given. With the exception of such quotations this dissertation is entirely my own work; I have acknowledged all main sources of help; If my research follows on from previous work or is part of a larger collaborative research pro-ject I have made clear exactly what was done by others and what I have contributed myself; I have read and understand the penalties associated with Academic Misconduct. I also confirm that I have obtained informed consent from all people I have involved in the...