Study of sulcal and anatomical landmarks variability in the inferior frontal lobe.

INTRODUCTION: The standard approach to asses the localization of fMRI activation areas in a group of subjects relies on the use of a proportional coordinate system such as Talairach space. Despite important development of spatial normalization techniques needed for that purpose, the problem of individual anatomical variability remains a limiting factor for precise localization of activation. The use of non-linear warping procedures to account for intersubject variability is becoming popular, but it may lack precision of individual gyri matching or may result in matching of non-corresponding gyri. An alternative approach to account fo