Coexistent Sarcoidosis and HIV Infection* A Comparison of Bronchoalveolar and

A case of pulmonary sarcoidosis diagnosed in a n human immunodeficiency virus (HIV)-infected m a n is reported. The transbronchial lung biopsy specimen revealed nonca-seating granuloma. A comparison of the lymphocyte subsets in both peripheral blood and bronchoalveolar lavage fluid revealed a pattern more typical of HIV infection than of classic sarcoidosis. A course of prednisone led to improve-ment in symptoms, roentgenographic findings, lung vol-umes, and diffusion capacity. (Chest 1992; 102:1899-1901) S arcoidosis is a disease of unknown cause that has an estimated prevalence in the United States of 5 pe r 100,000 whites and 40 pe r 100,000 nonwhites. ' The human immunodeficiency virus (HIV) type 1 is estimated to infect 1 million individuals in the United state^. ^ There have been only four cases of coexistent sarcoidosis and HIV infection reported in the English l i t e r a t ~ r e. ~. ~ To date and to ou