Journal of Rehabil itation Research & Development Word-retrieval treatment in aphasia: Effects of sentence context

Abstract—Word-retrieval treatment studies in aphasia have reported the greatest influences on picture naming for trained words. To increase treatment effects to untrained words and sentence contexts, we investigated a sentence-reading treat-ment hierarchy that moves from errorless to generative produc-tion of sentences incorporating target nouns and verbs. In an individual with nonfluent aphasia, treatment resulted in improved picture naming for nouns and verbs and generalized increases in numbers of grammatical sentences and content words following noun therapy. A second individual with fluent aphasia improved little in picture-naming and sentence-generation tasks for both nouns and verbs. This sentence-based word-retrieval training, in which semantic and syntactic processes are engaged, led to improvements in word-retrieval measures during spontaneous sentence generation, but only for the par-ticipant with nonfluent aphasia. Contrary to expectations, these changes were greater following noun therapy than they were following verb therapy